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Cognitive Enhancers and Memory
(Memory Enhancers) in recent decades have been gaining
increasing popularity. According to American
analysts market for memory enhancers and
human cognitive ability in the US is assessed
$ 1 billion a year.



PEMOLIN (magnesium pemoline, 2-amino-5-phenyl-4- (5H) oxazolone) – was considered at one time a very promising drug that can not only improve the ability to remember, but also significantly develop intellectual and creative abilities. In a daily dose of 50-100 mg after 2 months of administration, it causes a significant increase in IQ.
Belongs to the class of oxazolines. As a CNS stimulant, 5 times stronger than caffeine, but inferior to phenamine. Pemoline does not suppress appetite. Unlike amphetamines, it does not cause a pronounced sympathomimetic effect – palpitations, dry mouth, pupil dilation. Long-term use of pemoline can lead to mental dependence.


4-METHYLAMINOREX (Ice, Euphoria, U4Euh, dl-cis-2-amino-4-methyl-5-phenyl-2-oxazoline) is one of the relatively new and extremely dangerous street drugs. First synthesized by Poos G. in the early 60s. Like pemoline, it is an oxazoline derivative. Since the mid-80s, U4Euh has been gaining popularity among the American underground. Since 1987 officially banned in the United States. Due to the ease of synthesis from over-the-counter cold medicines, it is gaining more and more popularity in our country. This is facilitated by the opinion widespread among drug addicts that methylaminorex has a powerful stimulating effect on memory and intelligence. Most of those taking methylaminorex note an increase in the ability to solve both creative and routine tasks, an unprecedented clarity of thoughts. The effect lasts up to 16 hours.


CENTROFENOXIN (Deanol, Meclofenoxate) – can also be classified as “intelligence enhancers” and mild psychostimulants. Effective for the prevention of premature aging of the body. It prevents the accumulation of lipofuscin, a substance responsible for aging, in brain cells.
Prolongs the life of laboratory animals by 30%. The daily dose is up to 1500 mg per day. In Russia it is produced under the name Acefen (Acephenum)



PRL-8-53 (methyl 3- (2-benzylmethylaminoethyl) benzoic acid) is an outstanding memory enhancer. If an ordinary person is able to memorize within a second 7-8 of the presented numbers, then after taking PRL-8-53 – the ability to memorize increases 3 times! In the experiment, the subjects memorized up to 21-22 digits! In 1978, in a study of 30 college students, there was a 130-140% improvement in memorization! The effect lasts for about 7 hours. Cases of successful cure of amnesia after the first dose of the drug are described.

VAZOPRESSIN is a pituitary hormone marketed by Sandoz under the Diapid trademark. Improves both short-term and long-term memory, as well as the ability to concentrate and focus. Its use is advisable when it is necessary to assimilate a large amount of information. In predisposed subjects, it can cause euphoria and mental stimulation similar to cocaine. Apply as a nasal spray. It has a stimulating effect on the cardiovascular system, which can lead to such serious complications as heart attack, stroke or hypertensive crisis.


Bacopa monniera Linn extract. the popular name “brahmi” has a tonic effect, has a positive effect on memory and learning in people. Gotu kola is called the “grass of memory”. It has a calming effect on the central nervous system and is recommended for mental illness, schizophrenia, epilepsy, and nervous disorders. Improves cerebral circulation and oxygen supply to the brain, thereby increasing mental abilities, accelerating thinking processes, improving memory, potency, relieves headaches, has a mild diuretic (diuretic) effect.
Included in the preparations “FITOVIT”, “Gotu Kola”.

The drug from the seeds of the paniculata (Celastrus paniculatus) is used in India to rejuvenate the body, improve memory and mental abilities, and enhance sexual behavior. In mice, it increases the weight of the prostate and testes by 18-22%.



Here is just an incomplete list of substances that enhance intelligence and (or) facilitate memory: xanthinol nicotinate, phenozolone (Ordinator), idebenone (Iidebenone), Ginkgo biloba, acetyl-l-carnitine, DMAE, pyroglutamate (Pyroglutamate), ribonucleic acid (RNA) , phenylalanine, phenytoin (Dilantin), Ritalin, vitamin B-12, ACTH 4-10, niacin (Niacin), vitamin C, ginseng, GH3 (Gerovital), PRL-8-53, R-58-735, ISF- 2522, THA, metrazol and strychnine (the latter two are highly toxic).

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