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Bretazenil
Bretazenil

Bretazenil (Ro16-6028) is a benzodiazepine drug, a partial GABA agonist of benzodiazepine receptors. This drug was the most potent of the benzodiazepines studied, demonstrating compared to diazepam (91.1 nM), IC50 6.1 nM, compared to clonazepam (7.9 nM) and flunitrazepam (13.6 nM). Bretazenil was developed in 1988 as a highly effective anxiolytic drug and is classified as a high-potency benzodiazepine, from its administration there is less strong development of tolerance and withdrawal syndrome. Bretazenil differs from traditional 1,4-benzodiazepines in that it is a partial agonist and binds to α1, α2, α3, α4, α5 and α6 subunits, benzodiazepine GABA receptor complexes. Studies show that bretazenil has a positive effect on the body, unlike other benzodiazepines, demonstrates relaxation and sociability when taking the drug and there are no side effects such as depression, amnesia, nausea, loss of coordination, liver disease, brain damage. 0.5 mg of bretazenil is approximately comparable to 10 mg of diazepam. This drug can produce a pronounced sedative-hypnotic effect when taken independently and in combination with alcohol. This drug has never been commercialized and is sold only exclusively for research purposes, in special laboratories.

Bretazenil
Bretazenil
Synonyms
  • Bretazenil
  • Ro16-6028
IUPAC (13aS)-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, 1,1-dimethylethyl ester
Formula C19H20BrN3O3
Molecular weight 418.3
CAS 84379-13-5
Appearance Powder
Purity ≥ 98 %

Bretazenil and other chemicals sold on this website are for research and forensic medical examination.

The by-side physiological properties of Bretazenil are unknown.

Complete chemical formula Bretazen: (13aS)-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, 1,1-dimethylethyl ester.

Storage conditions of this chemical: in a cool and dry place. The stability of this chemical compound can last up to 2 years, under the right storage conditions.

Price:
1-4g NO

5-9g

24.00 EUR/g

5g 120.00 EUR

10-19g

20.00 EUR/g

10g 200 EUR

20-49g

16.00 EUR/g

20g 320 EUR

50-99g

9.00 EUR/g

50g 450 EUR

100-499g

7.50 EUR/g

100g 750 EUR

500+g

4.80 EUR/g

1k 4800 EUR

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What do you get when you buy a chemical on chemsline.com?

– A printed bag of aluminum foil containing a chemical of the first class Bretazenil.

Powder, over 98 % pure.

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