SR-17018(SR-17, SR and as 5,6-dichloro-desmethylchlorphine) is an opioid analgesic with an atypical modulator of the μ-opioid receptors. SR-17018 was first described in the scientific literature in 2017 by Laura Bohn and her colleagues. This drug demonstrates strong selectivity for activating the G protein signal over the β-arrestin2 set, causing fewer respiratory depressions than other opioid drugs such as heroin and fentanyl.
SR-17018 is 5,6-dichlorodesmethylchlorophine, a derivative of brorphine, chlorphine.
According to studies in rodents, SR-17018 has been found to act as a MOR agonist with almost irreversible binding to the receptor, which leads to constant signaling by the G protein as. It has a strong analgesic effect, practically does not cause respiratory depression in rodents.
This design preparation has an unclear legal status in many countries, as well as in the EU as a research substance. SR-17018 has an illegal status in Germany.
| Synonyms |
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| IUPAC | 5,6-dichloro-3-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one |
| Formula | C19H18Cl3N3O |
| Molecular weight | 410.72 g·mol−1 |
| CAS | 2134602-45-0 |
| Appearance | A crystalline solid |
| Purity | ≥ 98 % |
This chemical is intended for research and forensic work.
Adverse properties of SR-17018 have not been studied.
The complete chemical formula of SR-17018: 5,6-dichloro-3-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one.
Storage conditions of this chemical: in a cool and dry place. The stability of this chemical compound can last up to 2 years, under the right storage conditions.
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